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新奇事件簿 科學(xué)家發(fā)現(xiàn)抑郁分子

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2022年06月24日

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Scientists say they have discovered the part of the brain that is responsible for us feeling miserable, anxious and stressed. A UK-based medical research company called Heptares Therapeutics said it has located the molecule related to depression. It is a protein found inside the brain called CRF1. The company said the protein, "is important in regulating the body's response to stress and is implicated in stress-related diseases such as depression and anxiety". The team used one of the world's most powerful x-ray machines in its research. Lead researcher Fiona Marshall said a greater understanding of the CRF1 protein could lead to ground-breaking drugs to control depression.

科學(xué)家表示,他們發(fā)現(xiàn)了大腦中負(fù)責(zé)讓我們感到痛苦,焦慮和壓力的部分。位于英國(guó)的一家名叫Heptares Therapeutics的醫(yī)療研究公司表示,他們確定了與抑郁有關(guān)的分子的位置,大腦內(nèi)部一種叫作CRF1的蛋白質(zhì)。這家公司表示,這種蛋白質(zhì)“對(duì)于調(diào)控身體對(duì)壓力的反應(yīng)非常重要,與壓力有關(guān)的疾病有密切關(guān)聯(lián),比如抑郁和焦慮。”該小組在研究中使用了世界上最強(qiáng)大的X射線儀。首席研究人員Fiona Marshall表示,對(duì)CRF1蛋白質(zhì)更好的了解能夠促進(jìn)研發(fā)出控制抑郁的突破性藥物。

Britain's National Health Service (NHS) warned anyone suffering from depression or related illnesses not to get too excited about this research. It questioned whether a single molecule could really lead to depression, and said the condition actually resulted from a complex interaction of chemicals. An NHS statement expressed surprise at the way two of Britain's biggest newspapers have built the story up – "The Daily Mail" and "The Sunday Times". The latter reported that researchers had found the "miserable molecule," saying it was "the protein involved in all our feelings of stress, anxiety and even depression". The NHS said: "It's a great headline, but a hugely sweeping claim."

英國(guó)國(guó)民健康服務(wù)系統(tǒng)(NHS)警告任何患有抑郁癥或相關(guān)疾病的人都不要對(duì)這份研究過(guò)分激動(dòng)。該機(jī)構(gòu)質(zhì)疑單一的分子是否能夠造成抑郁。他們認(rèn)為抑郁癥實(shí)際上是由于各種化學(xué)物質(zhì)的相互作用。NHS一份聲明對(duì)英國(guó)兩家最大的報(bào)社宣揚(yáng)該研究的方式感到驚訝,分別是《每日郵報(bào)》和《星期日泰晤士報(bào)》。后者報(bào)道稱,研究人員發(fā)現(xiàn)了“痛苦分子”,稱這是“關(guān)系到我們所有壓力,焦慮甚至抑郁情緒的蛋白質(zhì)”。NHS表示:“這是個(gè)很吸引人的標(biāo)題,但是太夸大其詞了。”

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